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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC9A1
All Species:
21.82
Human Site:
Y683
Identified Species:
40
UniProt:
P19634
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P19634
NP_003038.2
815
90763
Y683
L
E
Q
K
I
N
N
Y
L
T
V
P
A
H
K
Chimpanzee
Pan troglodytes
XP_513239
793
88468
Y670
L
E
Q
K
I
N
N
Y
L
T
V
P
A
H
K
Rhesus Macaque
Macaca mulatta
XP_001115213
427
46791
V314
F
V
G
V
V
Y
G
V
I
A
A
F
T
S
R
Dog
Lupus familis
XP_535345
816
90951
Y684
L
E
Q
K
I
N
N
Y
L
T
V
P
A
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q61165
820
91449
Y687
L
E
Q
K
I
T
N
Y
L
T
V
P
A
H
K
Rat
Rattus norvegicus
P26431
820
91629
Y687
L
E
Q
K
I
T
N
Y
L
T
V
P
A
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514675
940
104115
R810
K
F
S
E
R
F
Q
R
K
N
N
M
P
H
S
Chicken
Gallus gallus
Q5ZJ75
574
64115
M461
L
L
L
G
G
G
T
M
P
L
I
R
L
I
G
Frog
Xenopus laevis
NP_001081553
781
87800
Y663
M
E
Q
R
V
T
N
Y
L
T
V
P
A
H
K
Zebra Danio
Brachydanio rerio
NP_001106952
653
73606
A540
S
T
T
S
L
S
S
A
A
T
Q
L
H
Q
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P35449
667
75263
I554
S
K
G
R
V
A
P
I
L
P
D
K
I
S
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWU6
535
59320
V422
T
A
T
T
A
I
V
V
L
T
V
L
L
I
G
Baker's Yeast
Sacchar. cerevisiae
Q04121
633
70130
Q520
L
L
N
G
S
S
I
Q
T
D
L
G
P
Y
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.3
51.9
95.8
N.A.
92.4
93.2
N.A.
42.5
21.7
73.2
55.4
N.A.
N.A.
N.A.
33.1
N.A.
Protein Similarity:
100
86.9
52
97.5
N.A.
95
95.1
N.A.
57.7
39.7
81.8
68.9
N.A.
N.A.
N.A.
52.5
N.A.
P-Site Identity:
100
100
0
100
N.A.
93.3
93.3
N.A.
6.6
6.6
73.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
93.3
N.A.
13.3
13.3
93.3
33.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.5
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
8
8
8
8
0
47
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% D
% Glu:
0
47
0
8
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
8
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
16
16
8
8
8
0
0
0
0
8
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
54
0
% H
% Ile:
0
0
0
0
39
8
8
8
8
0
8
0
8
16
0
% I
% Lys:
8
8
0
39
0
0
0
0
8
0
0
8
0
0
47
% K
% Leu:
54
16
8
0
8
0
0
0
62
8
8
16
16
0
0
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
24
47
0
0
8
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
8
0
8
8
0
47
16
0
0
% P
% Gln:
0
0
47
0
0
0
8
8
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
16
8
0
0
8
0
0
0
8
0
0
16
% R
% Ser:
16
0
8
8
8
16
8
0
0
0
0
0
0
16
16
% S
% Thr:
8
8
16
8
0
24
8
0
8
62
0
0
8
0
0
% T
% Val:
0
8
0
8
24
0
8
16
0
0
54
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
47
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _